TOP1

 Ensemble Search
ENSG00000198900 BioGRID Search
TOP1

Experiments

Targets ATAC-Seq CUT&Tag
H3K4me3 		CUT&Tag
H3K9me3 		CUT&Tag
MECP2-GFP 		CUT&Tag
RNA Pol II 		WGBS
NGN2-human neurons MECP2-WT WT_H3K4me3, WT_IgG WT_H3K9me3, WT_IgG WT, R133C, R168X, R270X, WT_IgG WT, R133C, R168X, R270X, WT_IgG MECP2-WT mCA, MECP2-WT mCG
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Human neuron RNA-Seq data (mRNA level)

MECP2.WT MECP2.KO MECP2.R133C MECP2.R168X
Replicate 3
9410.2900
2444.6400
1955.9200
1784.0600
Replicate 2
5070.9000
1933.1400
1175.8000
1387.2600
Replicate 1
7429.8600
1717.6600
1373.8000
1577.5300

Human neuron proteomic data (MECP2 AP-MS [Peptide intensity])

WT R133C R168X R270X
Replicate 1
1044402.9930
0.0000
8537559.0760
12836709.1600
Replicate 2
3173656.9720
4830435.3910
14822273.3300
16510978.1300
Replicate 3
7228571.4490
9554122.9640
10721724.9400
24766067.8000