NEDD4L

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NEDD4L

Experiments

Targets ATAC-Seq CUT&Tag
H3K4me3 		CUT&Tag
H3K9me3 		CUT&Tag
MECP2-GFP 		CUT&Tag
RNA Pol II 		WGBS
NGN2-human neurons MECP2-WT WT_H3K4me3, WT_IgG WT_H3K9me3, WT_IgG WT, R133C, R168X, R270X, WT_IgG WT, R133C, R168X, R270X, WT_IgG MECP2-WT mCA, MECP2-WT mCG
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Human neuron RNA-Seq data (mRNA level)

MECP2.WT MECP2.KO MECP2.R133C MECP2.R168X
Replicate 3
4727.2500
1161.8700
1101.3300
1137.2200
Replicate 2
3406.5900
1442.1400
858.6400
1420.0800
Replicate 1
2206.0400
1164.4000
805.3500
1533.1100

Human neuron proteomic data (MECP2 AP-MS [Peptide intensity])

WT R133C R168X R270X
Replicate 1
5563.9971
0.0000
25177.1302
0.0000
Replicate 2
43737.7414
43792.4868
50587.2793
30068.5115
Replicate 3
24038.3648
20592.7144
9109.3086
9121.0258