DSP

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DSP

Experiments

Targets ATAC-Seq CUT&Tag
H3K4me3 		CUT&Tag
H3K9me3 		CUT&Tag
MECP2-GFP 		CUT&Tag
RNA Pol II 		WGBS
NGN2-human neurons MECP2-WT WT_H3K4me3, WT_IgG WT_H3K9me3, WT_IgG WT, R133C, R168X, R270X, WT_IgG WT, R133C, R168X, R270X, WT_IgG MECP2-WT mCA, MECP2-WT mCG
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Human neuron RNA-Seq data (mRNA level)

MECP2.WT MECP2.KO MECP2.R133C MECP2.R168X
Replicate 3
244.8600
1697.7600
24.0700
74.7300
Replicate 2
243.3300
1853.9300
3.6800
77.9400
Replicate 1
148.6900
1332.9400
15.7000
66.3300

Human neuron proteomic data (MECP2 AP-MS [Peptide intensity])

WT R133C R168X R270X
Replicate 1
0.0000
0.0000
0.0000
0.0000
Replicate 2
91676.5127
69379.2664
30460.9422
136410.8865
Replicate 3
7698.6830
0.0000
0.0000
15230.6658